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Kamil Ugurbil, Ph.D.
Professor, Departments of Biochemistry, Radiology and Medicine
kamil@cmrr.umn.edu |
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Magnetic
resonance imaging and spectroscopy studies in cerebral function and
metabolism.
The primary focus of the ongoing research activity at the Center for
Magnetic Resonance Research (CMRR) is to develop techniques that will
permit novel use of high field magnetic resonance (MR) spectroscopy
and imaging, and apply these techniques to biomedical questions relevant
to basic physiological research and clinical medicine. Among the areas
targeted for human MR studies, the most important and prominent is
neurophysiology based on non-invasive functional imaging in the brain,
high-resolution and/or high contrast imaging of neuroanatomy, imaging
of perfusion, and finally spectroscopic studies of metabolism. This
laboratory has pioneered the development of non-invasive functional
imaging in the human brain using magnetic resonance techniques and
endogenous deoxyhemoglobin as an intrinsic contrast agent.
CMRR is equipped with state-of-the-art MR instruments. It has one
of the three 4 Tesla systems in the world capable of accommodating
humans, and has pioneered high field MR applications with humans.
CMRR also housed in March 1993 a first of its kind 9.4 Tesla system
which is large enough to work with medium-size animals. In addition,
a 4.7 Tesla/40 cm bore system is routinely used for animal studies.
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Selected Publications
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Olman CA, Ugurbil K, Schrater P, Kersten D BOLD fMRI and psychophysical measurements of contrast response to broadband images.
Vision Res. 2004 Mar;44(7):669-83 |
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Ugurbil K, Adriany G, Andersen P, Chen W, Garwood M, Gruetter R, Henry PG, Kim SG, Lieu H, Tkac I, Vaughan T, Van De Moortele PF, Yacoub E, Zhu XH Ultrahigh field magnetic resonance imaging and spectroscopy.
Magn Reson Imaging. 2003 Dec;21(10):1263-81 |
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Kim DS, Kim M, Ronen I, Formisano E, Kim KH, Ugurbil K, Mori S, Goebel R In vivo mapping of functional domains and axonal connectivity in cat visual cortex using magnetic resonance imaging.
Magn Reson Imaging. 2003 Dec;21(10):1131-40 |
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Lewis SM, Jerde TA, Tzagarakis C, Georgopoulos MA, Tsekos N, Amirikian B, Kim SG, Ugurbil K, Georgopoulos AP Cerebellar activation during copying geometrical shapes.
J Neurophysiol. 2003 Dec;90(6):3874-87 |
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Olman C, Ronen I, Ugurbil K, Kim DS Retinotopic mapping in cat visual cortex using high-field functional magnetic resonance imaging.
J Neurosci Methods. 2003 Dec 30;131(1-2):161-70 |
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Formisano E, Kim DS, Di Salle F, van de Moortele PF, Ugurbil K, Goebel R Mirror-symmetric tonotopic maps in human primary auditory cortex.
Neuron. 2003 Nov 13;40(4):859-69 |
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