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Bagrat
Amirikian, Ph.D.
Assistant Professor, Department of Neuroscience
amiri001@umn.edu |
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 Computations
in the Motor Cortex: Cortical Microcircuits, Functional Columns, and
Motor Control Signals.
Cortical processing is mediated through the short-range (local microcircuits)
and the long-range (interaction involving distinct microcircuits)
connections between excitatory and inhibitory neurons distributed
across distinct cortical layers. My current research interests are
focused on two problems. i. Whether do these spatially structured
intrinsic connections induce functional modularization of the motor
cortex (e.g., segregation of neurons with coherent properties into
columns), and how do they shape the computation of neural motor control
signals? ii. How does one translate neural signals extracted from
the motor cortex into signals appropriate for "intelligent" motor
control of prosthetic devices (e.g., multijoint robotic arm)? To investigate
these problems we use the methods of neural network modeling, and
carry out very large-scale simulations on high-performance massively
parallel supercomputers. |
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Selected Publications
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Lewis SM, Jerde TA, Tzagarakis C, Georgopoulos MA, Tsekos
N, Amirikian B, Kim SG, Ugurbil K, Georgopoulos AP
Cerebellar activation during copying geometrical shapes.
J
Neurophysiol. 2003 Dec;90(6):3874-87 |
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Amirikian B, Georgopoulos AP
Modular organization of directionally tuned cells in the motor cortex:
is there a short-range order?
Proc
Natl Acad Sci U S A. 2003 Oct 14;100(21):12474-9 |
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Amirikian B, Georgopoulos AP
Directional Operations in the Motor Cortex: Coding and Decoding. In:
The Handbook of Brain Theory and Neural Networks
(MIT Press Cambridge, MA; 2002) |
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Georgopoulos AP, Whang K, Georgopoulos MA, Tagaris
GA, Amirikian B, Richter W, Kim SG, Ugurbil K
Functional magnetic resonance imaging of visual object construction
and shape discrimination : relations among task, hemispheric lateralization,
and gender.
J
Cogn Neurosci. 2001 Jan 1;13(1):72-89 |
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Amirikian B, Georgopulos A
Directional tuning profiles of motor cortical cells
Neurosci
Res 2000 Jan;36(1):73-9 |
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Amirikian B, Georgopoulos AP
Cortical Populations and Behavior: Hebb's Thread.
Canadian
Journal of Experimental Psychology, 1999;53:21-34 |
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Amirikian B
Neural Networks and Modeling of Neuronal Networks.
In: Modern Techniques in Neuroscience Research, eds. U Windhorst,
H Johansson, Springer Heidelberg, 1999, pp. 689-704 |
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